Armanni Ebstein Lesion
Teaching Points

Armanni-Ebstein Lesion

Armanni-Ebstein lesion, originally described by Luciano Armanni in 1872, is characterized by vacuolization and PAS-positive glycogen accumulation within the cytoplasm…

The Kidneys and How They Work illustration
Patient Resources

The Kidneys and How They Work

Where are the kidneys and why do we need them? The kidneys are a pair of bean-shaped organs, each about…

Systemic Lupus Erythematosus, SLE, lupus nephritis, arkana laboratories, disease week, renal pathology
Disease Week

NIH Lupus Nephritis Activity and Chronicity Indices

NIH Lupus Nephritis Activity and Chronicity Indices: A way to monitor response to treatment and disease progression. A semi-quantitative grading…

Systemic Lupus Erythematosus, SLE, lupus nephritis, arkana laboratories, disease week, renal pathology
Disease Week

Introduction to Systemic Lupus Erythematosus and Clinical Diagnostic Criteria

Systemic lupus erythematosus (SLE) Systemic lupus erythematosus (SLE) is a systemic autoimmune disease which affects over 5 million people worldwide,…

illustration representing Diabetes Mellitus
Patient Resources

Diabetes Mellitus

What is diabetes mellitus? Diabetes mellitus, or simply diabetes, is a metabolic disease that results in high blood sugar, either…

Armanni Ebstein Lesion
Teaching Points

Armanni-Ebstein Lesion

Armanni-Ebstein lesion, originally described by Luciano Armanni in 1872, is characterized by vacuolization and PAS-positive glycogen accumulation within the cytoplasm…

The Kidneys and How They Work illustration
Patient Resources

The Kidneys and How They Work

Where are the kidneys and why do we need them? The kidneys are a pair of bean-shaped organs, each about…

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Kidneys for Kids abstract illustration
Patient Resources

Kidneys for Kids

What are the kidneys and what do they do? Your kidneys are organs shaped like beans (think kidney beans) and…

Neuromuscular Junction, NMJ, Neuro Pathology, myoneural junction, motor end-plate
Neuro Notes

The Neuromuscular Junction

What is the dark staining structure? (Hint: note the small nerve twig associated with the structure). The neuromuscular junction (NMJ;…

By Kelly Mrachek, MD
Subepithelial Humps, irregular subepithelial deposits
Teaching Points

Subepithelial Humps

  The depicted electron micrograph shows numerous, large and irregular subepithelial deposits which protrude from the glomerular basement membrane towards…


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Diagnose This!

Diagnose This 4/29/2024

What would be your leading Dx and subtype based on the Congo red image above showing deposition predominately in the…

Diagnose This!

Diagnose This 4/15/2024

Based on the image provided, what would be your leading diagnosis with C3-dominant immune-complex deposition? The light microscopic image depicts…

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Diagnose This 4/1/2024

What is this finding and what is the significance in the transplant setting?   The light microscopic image depicts an…

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LDL Receptor-Related Protein 2