Joshua Sonnen

Joshua Sonnen, MD Neuropathologist

About

Joshua Sonnen, MD joined the Physician Team at Arkana Labs in September 2022 as a neuropathologist. Dr. Sonnen received his MD from the Keck School of Medicine, at the University of Southern California in Los Angeles, CA. He completed his pathology residency at the University of Arizona in Tucson, AZ in 2005, and his neuropathology fellowship at the University of Washington in Seattle, WA in 2007. Prior to working at Arkana, Dr. Sonnen was as an Associate Professor and Director of Neuroautopsy at McGill University, and an associate in the Department of Neurology and Neurosurgery at the Montreal Neurological Hospital & Institute in Montreal, QC. Dr. Sonnen held previous academic appointments at the University of Utah and the University of Washington. His research interests include age-related neuropathology, neurodegenerative disorders, neuroepidemiology and genetics, and the disease-modifying potential for drug and lifestyle exposures.

 

Dr. Joshua Sonnen is board certified in anatomic pathology and neuropathology. He is a member of the Association of American Pathologists, the International Society of Neuropathology, the International Society of Vascular Behavioural and Cognitive Disorders, and the College of American Pathologists.

Education & Stats

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Joined the Arkana Team 2022
Doctor of Medicine University of Southern California, Los Angeles
Pathology Residency University of Arizona, Tucson
Neuropathology Fellowship University of Washington, Seattle
Board of Certification American Board of Pathology in Anatomic Pathology and Neuropathology

Featured Publications by Joshua Sonnen, M.D.

Pathological Correlates Of Dementia In A Longitudinal, Population-Based Sample Of… Pathological Correlates Of Dementia In A…

By Sonnen JA, Larson EB, Crane PK, Haneuse S, Li G, Schellenberg GD, Craft S, Leverenz JB, Montine TJ

October 2007

Previously published community- or population-based studies of brain aging and dementia with autopsy were restricted to…

Previously published community- or population-based studies of brain aging and dementia with autopsy were restricted to a single sex, a single ethnic group, Roman Catholic clergy, or focused pathological assessments. Our goal was to determine the…

Read on PubMed

18F-MK-6240 tau-PET In Genetic Frontotemporal Dementia 18F-MK-6240 tau-PET In Genetic Frontotemporal…

By Levy J, Savard M, Pascoal T, Bezgin G, Finger E, Laforce R, Sonnen JA, Soucy J-P, Gauthier S, Rosa-Neto P, Ducharme S

June 2022

Tau is one of several proteins associated with frontotemporal dementia. While knowing which protein is causing a…

Tau is one of several proteins associated with frontotemporal dementia. While knowing which protein is causing a patient's disease is crucial, no biomarker currently exists for identifying tau in vivo in frontotemporal dementia.

Read on PubMed

Theoretical Impact Of The AT(N) Framework On Dementia Using A Community Autopsy… Theoretical Impact Of The AT(N) Framework On…

By Burke BT, Latimer C, Keene CD, Montine TJ, Sonnen JA, McCormick W, Bown JD, McCurry SM, Larson EB, Crane PK

December 2021

The AT(N) research framework categorizes eight biomarker profiles using amyloid (A), tauopathy (T), and…

The AT(N) research framework categorizes eight biomarker profiles using amyloid (A), tauopathy (T), and neurodegeneration (N), regardless of dementia status.

Read on PubMed

Vessel Wall Enhancement On Black-Blood Mri Predicts Acute And Future Stroke In… Vessel Wall Enhancement On Black-Blood Mri…

By McNally JS, Sakata A, Alexander MD, Dewitt LD, Sonnen JA, Menacho ST, Stoddard GJ, Kim SE, de Havenon AH

June 2021

Cerebral amyloid angiopathy (CAA) is a known risk factor for ischemic stroke though angiographic imaging is often…

Cerebral amyloid angiopathy (CAA) is a known risk factor for ischemic stroke though angiographic imaging is often negative. Our goal was to determine the relationship between vessel wall enhancement (VWE) in acute and future ischemic stroke in CAA…

Read on PubMed

International Consortium on the Genetics of Electroconvulsive Therapy and Severe… International Consortium on the Genetics of…

By Soda T, McLoughlin DM, Clark SR, Oltedal L, Kessler U, Haavik J, Bousman C, Smith DJ, Bioque M, Clements CC, Loo C, Vila-Rodriguez F, Minelli A, Mickey BJ, Milev R,…

October 2020

Recent genome-wide association studies have demonstrated that the genetic burden associated with depression correlates…

Recent genome-wide association studies have demonstrated that the genetic burden associated with depression correlates with depression severity. Therefore, conducting genetic studies of patients at the most severe end of the depressive disorder…

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