Featured Publications
About Our Research
We’ve doubled down on our commitment to research and teaching.
Arkana is a learning, teaching, and innovating practice with one unifying passion – to actively work toward the day that our research yields breakthroughs that make our services unnecessary. Eradicating rare and common diseases is the end game of all of our efforts because patient health is foremost in our minds every day. Read about some of our latest publications below.
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All Publications
(453 Results)
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The Kidney Biopsy in Systemic Lupus Erythematosus: A View of the Past and a Vision of the Future
The kidney biopsy advanced our understanding of kidney disease in systemic lupus erythematosus. It allowed for better recognition and classification…
Read on PubMed• September 2019
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Renal And Pulmonary Thrombotic Microangiopathy Triggered By Proteasome-Inhibitor Therapy In Patient With Smoldering Myeloma: A Renal Biopsy And Autopsy Case Report
Thrombotic microangiopathy (TMA) is a group of clinical syndromes characterized by excessive platelet activation and endothelial injury that leads to…
Read on PubMed• September 2019
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Eculizumab Deposits In Vessel Walls In Thrombotic Microangiopathy
Terminal complement inhibition therapy with eculizumab (a humanized monoclonal antibody to C5) has revolutionized the treatment of patients with thrombotic…
Read on PubMed• September 2019
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Cell-Type Specific Differences In Antiretroviral Penetration And The Effects Of HIV-1 Tat And Morphine Among Primary Human Brain Endothelial Cells, Astrocytes, Pericytes, And Microglia
The inability to achieve adequate intracellular antiretroviral concentrations may contribute to HIV persistence within the brain and to neurocognitive deficits…
Read on PubMed• September 2019
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Anti-LRP2 Nephropathy With Abundant IgG4-Positive Plasma Cells: A Case Report
In older adults, the most common kidney biopsy diagnoses include pauci-immune crescentic glomerulonephritis, membranous nephropathy, and focal segmental glomerulosclerosis.
Read on PubMed• July 2019
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Anti-PD-1 Immunotherapy May Induce Interstitial Nephritis With Increased Tubular Epithelial Expression Of PD-L1
Novel anticancer therapies include anti-programmed cell death protein-1 (PD-1) and anti-programmed death ligand-1 (PD-L1) drugs.
Read on PubMed• June 2019
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Patient With A Prkag2 Mutation Who Developed Immunoglobulin A Nephropathy: A Case Report
PRKAG2 syndrome (PS) is a rare, early-onset autosomal dominant inherited disease caused by mutations in PRKAG2, the gene encoding the…
Read on PubMed• June 2019
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HIV-1 Tat And Opioids Act Independently To Limit Antiretroviral Brain Concentrations And Reduce Blood-Brain Barrier Integrity
Poor antiretroviral penetration may contribute to human immunodeficiency virus (HIV) persistence within the brain and to neurocognitive deficits in opiate…
Read on PubMed• May 2019
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Urine TNF-Α And IL-9 For Clinical Diagnosis Of Acute Interstitial Nephritis
Clinical diagnosis of acute interstitial nephritis (AIN) is challenging because of lack of a diagnostic biomarker and requires a kidney…
Read on PubMed• May 2019
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Patrolling Monocytes Promote The Pathogenesis Of Early Lupus-Like Glomerulonephritis
Systemic lupus erythematosus (SLE) is a complex autoimmune disease with genetic and environmental contributions.
Read on PubMed• April 2019
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