Featured Publications
About Our Research
We’ve doubled down on our commitment to research and teaching.
Arkana is a learning, teaching, and innovating practice with one unifying passion – to actively work toward the day that our research yields breakthroughs that make our services unnecessary. Eradicating rare and common diseases is the end game of all of our efforts because patient health is foremost in our minds every day. Read about some of our latest publications below.
All Publications
(453 Results)
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Infantile Nephrocalcinosis Resulting From A Pathogenic CYP24A1 Mutation
Hypercalcemia is a rare finding in children but is most common in neonates. Unlike adults, in whom the vast majority…
Read on PubMed• April 2019
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Effect Of Chemotherapy On Cancer Stem Cells And Tumor-Associated Macrophages In A Prospective Study Of Preoperative Chemotherapy In Soft Tissue Sarcoma
This study examined the expression of the putative cancer stem cell markers ALDH1, CD44, and CD133; the angiogenesis marker CD31;…
Read on PubMed• April 2019
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Effects Of HIV-1 Tat On Oligodendrocyte Viability Are Mediated By Camkiiβ-Gsk3β Interaction
Myelin disruptions are frequently reported in human immunodeficiency virus (HIV)-infected individuals and can occur in the CNS very early in…
Read on PubMed• March 2019
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The Contribution Of The Rs55705857 G Allele To Familial Cancer Risk As Estimated In The Utah Population Database
IDH1/2 mutated glioma has been associated with a germline risk variant, the rs55705857 G allele. The Utah Population Database (UPDB),…
Read on PubMed• March 2019
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Donor-Derived Philadelphia Chromosome-Positive B Cell Lymphoblastic Leukemia Presenting With Renal Allograft Involvement In The First Year Post Transplant
Donor malignancy transmission is a rare but well-recognized solid organ transplantation complication that carries high mortality risk. Here, we report…
Read on PubMed• March 2019
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Ccr5 Mediates HIV-1 Tat-Induced Neuroinflammation And Influences Morphine Tolerance, Dependence, And Reward
The HIV-1 regulatory protein, trans-activator of transcription (Tat), interacts with opioids to potentiate neuroinflammation and neurodegeneration within the CNS. These…
Read on PubMed• March 2019
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Complete Biopsy-Proven Resolution Of Deposits In Recurrent Proliferative Glomerulonephritis With Monoclonal Igg Deposits (Pgnmigd) Following Rituximab Treatment In Renal Allograft
Proliferative glomerulonephritis with monoclonal IgG deposits (PGNMIGD) is a disease entity classified under the group of “Monoclonal gammopathy-related kidney diseases”,…
Read on PubMed• February 2019
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CNS Inflammation And Neurodegeneration: Sequelae Of Peripheral Inoculation With Spinal Cord Tissue In Rat
Recent research demonstrates that victims of spinal cord injury (SCI) are at increased risk for dementia and that encephalitis can…
Read on PubMed• February 2019
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Characterization Of Cell-Cell Junction Changes Associated With The Formation Of A Strong Endothelial Barrier
A principal function of endothelial cells is the formation of a barrier between the blood and tissues. This barrier arises…
Read on PubMed• February 2019
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Role Of Meprin Metalloproteinases In Cytokine Processing And Inflammation
Meprin metalloendopeptidases, comprising and isoforms, are widely expressed in mammalian cells and organs including kidney, intestines, lungs, skin,…
Read on PubMed• February 2019