Featured Publications
About Our Research
We’ve doubled down on our commitment to research and teaching.
Arkana is a learning, teaching, and innovating practice with one unifying passion – to actively work toward the day that our research yields breakthroughs that make our services unnecessary. Eradicating rare and common diseases is the end game of all of our efforts because patient health is foremost in our minds every day. Read about some of our latest publications below.
All Publications
(475 Results)
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Patient With A Prkag2 Mutation Who Developed Immunoglobulin A Nephropathy: A Case Report
PRKAG2 syndrome (PS) is a rare, early-onset autosomal dominant inherited disease caused by mutations in PRKAG2, the gene encoding the…
Read on PubMed• June 2019
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HIV-1 Tat And Opioids Act Independently To Limit Antiretroviral Brain Concentrations And Reduce Blood-Brain Barrier Integrity
Poor antiretroviral penetration may contribute to human immunodeficiency virus (HIV) persistence within the brain and to neurocognitive deficits in opiate…
Read on PubMed• May 2019
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Urine TNF-Α And IL-9 For Clinical Diagnosis Of Acute Interstitial Nephritis
Clinical diagnosis of acute interstitial nephritis (AIN) is challenging because of lack of a diagnostic biomarker and requires a kidney…
Read on PubMed• May 2019
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Patrolling Monocytes Promote The Pathogenesis Of Early Lupus-Like Glomerulonephritis
Systemic lupus erythematosus (SLE) is a complex autoimmune disease with genetic and environmental contributions.
Read on PubMed• April 2019
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Infantile Nephrocalcinosis Resulting From A Pathogenic CYP24A1 Mutation
Hypercalcemia is a rare finding in children but is most common in neonates. Unlike adults, in whom the vast majority…
Read on PubMed• April 2019
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Effect Of Chemotherapy On Cancer Stem Cells And Tumor-Associated Macrophages In A Prospective Study Of Preoperative Chemotherapy In Soft Tissue Sarcoma
This study examined the expression of the putative cancer stem cell markers ALDH1, CD44, and CD133; the angiogenesis marker CD31;…
Read on PubMed• April 2019
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Effects Of HIV-1 Tat On Oligodendrocyte Viability Are Mediated By Camkiiβ-Gsk3β Interaction
Myelin disruptions are frequently reported in human immunodeficiency virus (HIV)-infected individuals and can occur in the CNS very early in…
Read on PubMed• March 2019
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The Contribution Of The Rs55705857 G Allele To Familial Cancer Risk As Estimated In The Utah Population Database
IDH1/2 mutated glioma has been associated with a germline risk variant, the rs55705857 G allele. The Utah Population Database (UPDB),…
Read on PubMed• March 2019
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Donor-Derived Philadelphia Chromosome-Positive B Cell Lymphoblastic Leukemia Presenting With Renal Allograft Involvement In The First Year Post Transplant
Donor malignancy transmission is a rare but well-recognized solid organ transplantation complication that carries high mortality risk. Here, we report…
Read on PubMed• March 2019
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Ccr5 Mediates HIV-1 Tat-Induced Neuroinflammation And Influences Morphine Tolerance, Dependence, And Reward
The HIV-1 regulatory protein, trans-activator of transcription (Tat), interacts with opioids to potentiate neuroinflammation and neurodegeneration within the CNS. These…
Read on PubMed• March 2019
