Featured Publications
About Our Research
We’ve doubled down on our commitment to research and teaching.
Arkana is a learning, teaching, and innovating practice with one unifying passion – to actively work toward the day that our research yields breakthroughs that make our services unnecessary. Eradicating rare and common diseases is the end game of all of our efforts because patient health is foremost in our minds every day. Read about some of our latest publications below.
All Publications
(453 Results)
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Exposure to Strong Anticholinergic Medications and Dementia-Related Neuropathology in a Community-Based Autopsy Cohort
Anticholinergic medication exposure has been associated with increased risk for dementia. No study has examined the association between anticholinergic medication…
Read on PubMed• June 2018
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Susceptibility To Neurofibrillary Tangles: Role Of The PTPRD Locus And Limited Pleiotropy With Other Neuropathologies
Tauopathies, including Alzheimer’s disease (AD) and other neurodegenerative conditions, are defined by a pathological hallmark: neurofibrillary tangles (NFTs). NFT accumulation…
Read on PubMed• June 2018
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Reduced Intraepidermal Nerve Fibre Density, Glial Activation, And Sensory Changes In HIV Type-1 Tat-Expressing Female Mice: Involvement Of Tat During Early Stages Of HIV-Associated Painful Sensory Neuropathy
HIV infection is associated with chronic pain states, including sensory neuropathy, which affects greater than 40% of patients.
Read on NLM• May 2018
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Mutant IDH1 Promotes Glioma Formation In Vivo
Isocitrate dehydrogenase 1 (IDH1) is the most commonly mutated gene in grade II-III glioma and secondary glioblastoma (GBM). A causal…
Read on PubMed• May 2018
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The Role Of The Immune System In Kidney Disease
The immune system and the kidneys are closely linked. In health the kidneys contribute to immune homeostasis, while components of…
Read on PubMed• May 2018
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Lipopolysaccharide Endotoxemia Induces Amyloid-Β And P-Tau Formation In The Rat Brain
Amyloid beta (A) plaques are not specific to Alzheimer’s disease and occur with aging and neurodegenerative disorders. Soluble brain A…
Read on PubMed• April 2018
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Tissue Staining For Thsd7a In Glomeruli Correlates With Serum Antibodies In Primary Membranous Nephropathy: A Clinicopathological Study
Thrombospondin type-1 domain-containing 7A (THSD7A) is the most recently recognized target antigen in patients with membranous nephropathy.
Read on PubMed• April 2018
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An Integrated Pathology And Ultrasonography-Based Simulation For Training In Performing Kidney Biopsy
A novel KBSW is an effective educational tool to acquire proficiency in PKB performance and could help regain interest among…
Read on PubMed• March 2018
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Genetic Testing Of Complement And Coagulation Pathways In Patients With Severe Hypertension And Renal Microangiopathy
A diagnosis of thrombotic microangiopathy on kidney biopsy in a patient presenting with hypertensive emergency has historically elicited the diagnosis…
Read on PubMed• March 2018
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Ldl Receptor-Related Protein 2 (Megalin) As A Target Antigen In Human Kidney Anti-Brush Border Antibody Disease
Primary renal tubulointerstitial disease resulting from proximal tubule antigen-specific antibodies and immune complex formation has not been well characterized in…
Read on PubMed• February 2018