Featured Publications
About Our Research
We’ve doubled down on our commitment to research and teaching.
Arkana is a learning, teaching, and innovating practice with one unifying passion – to actively work toward the day that our research yields breakthroughs that make our services unnecessary. Eradicating rare and common diseases is the end game of all of our efforts because patient health is foremost in our minds every day. Read about some of our latest publications below.

All Publications
(476 Results)
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Assessment Of The Genetic Variance Of Late-Onset Alzheimer’s Disease
Alzheimer’s disease (AD) is a complex genetic disorder with no effective treatments. More than 20 common markers have been identified,…
Read on PubMed• May 2016
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Importance Of Home Study Visit Capacity In Dementia Studies
The importance of home research study visit capacity in Alzheimer’s disease (AD) studies is unknown.
Read on PubMed• April 2016
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Neuropathologic Comorbidity And Cognitive Impairment In The Nun And Honolulu-Asia Aging Studies
Objective: To examine frequencies and relationships of 5 common neuropathologic abnormalities identified at autopsy with late-life cognitive impairment and dementia…
Read on PubMed• March 2016
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Expanding the Spectrum of Renal Tumors in Children: Primary Renal Myoepithelial Carcinomas With a Novel EWSR1-KLF15 Fusion
We report the first 2 examples of primary renal myoepithelial carcinoma (MEC), both occurring in children. Both tumors had the…
Read on PubMedExpanding the Spectrum of Renal Tumors in Children: Primary Renal Myoepithelial Carcinomas With a Novel EWSR1-KLF15 Fusion •
• March 2016
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Alzheimer’s Disease Risk Polymorphisms Regulate Gene Expression In The ZCWPW1 And The CELF1 Loci
Late onset Alzheimer’s disease (LOAD) is a genetically complex and clinically heterogeneous disease. Recent large-scale genome wide association studies (GWAS)…
Read on PubMed• February 2016
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Central HIV-1 Tat Exposure Elevates Anxiety And Fear Conditioned Responses Of Male Mice Concurrent With Altered Mu-Opioid Receptor-Mediated G-Protein Activation And Β-Arrestin 2 Activity In The Forebrain
Co-exposure to opiates and HIV/HIV proteins results in enhanced CNS morphological and behavioral deficits in HIV(+) individuals and in animal…
Read on PubMed• February 2016
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Multisite Assessment Of NIA-AA Guidelines For The Neuropathologic Evaluation Of Alzheimer’s Disease
Neuropathologic assessment is the current “gold standard” for evaluating the Alzheimer’s disease (AD), but there is no consensus on the…
Read on PubMed• February 2016
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Cerebral Amyloid Angiopathy-Related Inflammation: A Potentially Reversible Cause Of Dementia With Characteristic Imaging Findings
Cerebral amyloid angiopathy with inflammation (CAA-I) is a less well-recognized clinically and radiologically distinct subtype of CAA.
Read on PubMed• February 2016
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5α-Reduced Progestogens Ameliorate Mood-Related Behavioral Pathology, Neurotoxicity, And Microgliosis Associated With Exposure To HIV-1 Tat
Human immunodeficiency virus (HIV) is associated with motor and mood disorders, likely influenced by reactive microgliosis and subsequent neural damage.…
Read on PubMed• January 2016
