Featured Publications
About Our Research
We’ve doubled down on our commitment to research and teaching.
Arkana is a learning, teaching, and innovating practice with one unifying passion – to actively work toward the day that our research yields breakthroughs that make our services unnecessary. Eradicating rare and common diseases is the end game of all of our efforts because patient health is foremost in our minds every day. Read about some of our latest publications below.
All Publications
(475 Results)
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Identification and validation of urinary CXCL9 as a biomarker for diagnosis of acute interstitial nephritis
Acute tubulointerstitial nephritis (AIN) is one of the few causes of acute kidney injury with diagnosis-specific treatment options. However, due…
Read on JCI• July 2023
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Clinicopathological Characteristics of Adult IgA Nephropathy in the United States
IgA nephropathy (IgAN) is a progressive autoimmune kidney disease and a leading cause of glomerular disease that can result in…
Read on kirereports.org• June 2023
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Clinicopathologic Spectrum of Lysozyme-Associated Nephropathy
Lysozyme-associated nephropathy (LyN), a rare cause of kidney injury in patients with chronic myelomonocytic leukemia (CMML), has not been well…
Read on kirereports.org• May 2023
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The association of low birthweight and prematurity on outcomes in children and adults with nephrotic syndrome-a NEPTUNE cohort study
In single-center studies, both preterm birth and low birth weight (LBW) are associated with worse outcomes in childhood nephrotic syndrome.…
Read on Springer Link• May 2023
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Proprotein convertase subtilisin/kexin type 6 (PCSK6) is a likely antigenic target in membranous nephropathy and nonsteroidal anti-inflammatory drug use
Drugs are an important secondary cause of membranous nephropathy (MN) with the most common drugs associated with MN being nonsteroidal…
Read on Kidney International• April 2023
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COVID-19 Vaccination and New Onset Glomerular Disease: Results from the IRocGN2 International Registry
IgAN and MCD are the most common de novo glomerular diseases reported after COVID-19 vaccination, particularly after mRNA vaccination. Membranous…
Read on Kidney 360• March 2023
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False-positive anti-PLA2R ELISA testing in patients with diabetes mellitus
We identified 2 similar patients with biopsy-proven diabetic nephropathy with false-positive phospholipase A2 receptor (PLA2R) testing by enzyme-linked immunosorbent assay…
Read on Kidney International• February 2023
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Glomerular diseases post-hematopoietic stem cell transplantation: pathologic spectrum and plausible mechanisms
Haematopoietic stem cell transplantation (HSCT) can be a life-saving, curative treatment for patients with hematologic malignancies and hematologic disorders, with…
Read on Oxford Academic• February 2023
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Self-Renewing CD8+ T-cell Abundance in Blood Associates with Response to Immunotherapy
Treatment with immune checkpoint blockade (ICB) often fails to elicit durable antitumor immunity. Recent studies suggest that ICB does not…
Read on AACR Journals• February 2023
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Serologic Studies in Membranous Nephropathy: Novel Strategies and Strengthened Associations
Serologic studies have transformed clinical practice for patients with phospholipase A2 receptor (PLA2R)-positive membranous nephropathy (MN) by enabling noninvasive therapeutic…
Read on Kidney 360• February 2023