Featured Publications
About Our Research
We’ve doubled down on our commitment to research and teaching.
Arkana is a learning, teaching, and innovating practice with one unifying passion – to actively work toward the day that our research yields breakthroughs that make our services unnecessary. Eradicating rare and common diseases is the end game of all of our efforts because patient health is foremost in our minds every day. Read about some of our latest publications below.
All Publications
(475 Results)
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Monoclonal Igg1κ Anti-Glomerular Basement Membrane Disease: A Case Report
We report a case of anti-glomerular basement membrane (anti-GBM) nephritis with indolent course, monoclonal IgG1 (immunoglobulin G, subclass 1, …
Read on PubMed• February 2015
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Paraffin Immunofluorescence In The Renal Pathology Laboratory: More Than A Salvage Technique
Immunofluorescence studies on paraffin-embedded tissue after Pronase digestion (paraffin immunofluorescence) is used as a salvage technique in renal pathology, when…
Read on PubMed• February 2015
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Cerebral Cortical Aβ42 And PHF-Τ In 325 Consecutive Brain Autopsies Stratified By Diagnosis, Location, And APOE
We used a novel approach to molecular quantification in standard fixed and embedded tissue to measure amyloid 42 (A(42))…
Read on PubMed• February 2015
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Rarity Of The Alzheimer Disease-Protective APP A673T Variant In The United States
Recently, a rare variant in the amyloid precursor protein gene (APP) was described in a population from Iceland. This variant,…
Read on PubMed• February 2015
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Human Udp-Glucuronosyltransferases: Effects Of Altered Expression In Breast And Pancreatic Cancer Cell Lines
Increased aerobic glycolysis and de novo lipid biosynthesis are common characteristics of invasive cancers.
Read on PubMed• January 2015
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Histopathologic Findings Associated With APOL1 Risk Variants In Chronic Kidney Disease
Compared with populations who lack recent African ancestry, African Americans have higher incidence rates of chronic kidney disease (CKD).Two coding…
Read on PubMed• January 2015
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Endothelin-1 Upregulation Mediates Aging-Related Cardiac Fibrosis
Endothelin-1 (ET-1) plays a major role in regulating myocardial fibrosis in several pathological conditions, such as hypertension and diabetes.
Read on PubMed• January 2015
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Apolipoprotein L1-Associated Nephropathy And The Future Of Renal Diagnostics
Apolipoprotein L1 (APOL1)-associated nephropathies comprise a spectrum of related nondiabetic kidney diseases strongly associated with the G1 and G2 coding…
Read on PubMed• January 2015
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Didehydro-Cortistatin A Inhibits HIV-1 Tat Mediated Neuroinflammation And Prevents Potentiation Of Cocaine Reward In Tat Transgenic Mice
HIV-1 Tat protein has been shown to have a crucial role in HIV-1-associated neurocognitive disorders (HAND), which includes a group…
Read on NLM• January 2015
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Conditional Tat Protein Brain Expression In The GT-Tg Bigenic Mouse Induces Cerebral Fractional Anisotropy Abnormalities
Cerebral white matter changes including tissue water diffusion abnormalities detected with diffusion tensor magnetic resonance imaging (DTI) are commonly found…
Read on PubMed• January 2015