Featured Publications
About Our Research
We’ve doubled down on our commitment to research and teaching.
Arkana is a learning, teaching, and innovating practice with one unifying passion – to actively work toward the day that our research yields breakthroughs that make our services unnecessary. Eradicating rare and common diseases is the end game of all of our efforts because patient health is foremost in our minds every day. Read about some of our latest publications below.
All Publications
(475 Results)
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Male Microchimerism In The Human Female Brain
In humans, naturally acquired microchimerism has been observed in many tissues and organs. Fetal microchimerism, however, has not been investigated…
Read on PubMed• September 2012
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Metabolic Regulation Of Organelle Homeostasis In Lupus T Cells
Abnormal T-cell signaling and activation are characteristic features in systemic lupus erythematosus (SLE). Lupus T cells are shifted toward an…
Read on PubMed• September 2012
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N-Acetylcysteine Reduces Disease Activity By Blocking Mammalian Target Of Rapamycin In T Cells From Systemic Lupus Erythematosus Patients: A Randomized, Double-Blind, Placebo-Controlled Trial
Systemic lupus erythematosus (SLE) patients exhibit T cell dysfunction, which can be regulated through mitochondrial transmembrane potential (m) and mammalian…
Read on PubMed• September 2012
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Case Report: Eculizumab Rescue Of Severe Accelerated Antibody-Mediated Rejection After Abo-Incompatible Kidney Transplant
ABO-incompatible (ABOI) living donor kidney transplantation has become a well-accepted practice with standard protocols using perioperative antibody-depleting therapies to lower…
Read on PubMed• September 2012
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Novel Antibody Capture Assay For Paraffin-Embedded Tissue Detects Wide-Ranging Amyloid Beta And Paired Helical Filament-Tau Accumulation In Cognitively Normal Older Adults
Quantifying antigens in formalin-fixed tissue is challenging and limits investigation in population-based studies of brain aging.
Read on PubMed• July 2012
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Adult Changes In Thought Study: Dementia Is An Individually Varying Convergent Syndrome With Prevalent Clinically Silent Diseases That May Be Modified By Some Commonly Used Therapeutics
The Adult Changes in Thought (ACT) study is a longitudinal population-based prospective cohort study of brain aging and incident dementia…
Read on PubMed• July 2012
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Brain Expression Genome-Wide Association Study (eGWAS) Identifies Human Disease-Associated Variants
Genetic variants that modify brain gene expression may also influence risk for human diseases. We measured expression levels of 24,526…
Read on PubMed• June 2012
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Occult Tumors Presenting With Negative Imaging: Analysis Of The Literature
Some patients presenting with neurological symptoms and normal findings on imaging studies may harbor occult brain tumors that are undetectable…
Read on PubMed• June 2012
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Extensive Extramedullary Disease Involving The Colon In Multiple Myeloma: A Case Report And Review Of Literature
Organ involvement in multiple myeloma (MM) is characterized by infiltrative disease or by a myelomatous mass known as a plasmacytoma.
Read on PubMed• June 2012
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Persistent Or New Onset Microscopic Hematuria In Patients With Small Vessel Vasculitis In Remission: Findings On Renal Biopsy
Hematuria is considered a sign of active renal disease in patients with small-vessel vasculitis. In patients who are in apparent…
Read on PubMed• June 2012
