Featured Publications
About Our Research
We’ve doubled down on our commitment to research and teaching.
Arkana is a learning, teaching, and innovating practice with one unifying passion – to actively work toward the day that our research yields breakthroughs that make our services unnecessary. Eradicating rare and common diseases is the end game of all of our efforts because patient health is foremost in our minds every day. Read about some of our latest publications below.
All Publications
(475 Results)
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Apol1 Risk Variants Predict Histopathology And Progression To Esrd In Hiv-Related Kidney Disease
With earlier institution of antiretroviral therapy, kidney diseases other than HIV-associated nephropathy (HIVAN) predominate in HIV-infected persons.
Read on PubMed• December 2011
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Intrapancreatic Accessory Spleen: Investigative Dilemmas And Role Of Eus-Guided Fna For Diagnostic Confirmation
A 33-year-old patient with history of dyspepsia underwent imaging studies suggestive of a neuroendocrine tumor. After referral to our institute,…
Read on PubMed• November 2011
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I. Levels Of 5α-Reduced Progesterone Metabolite In The Midbrain Account For Variability In Reproductive Behavior Of Middle-Aged Female Rats
At middle-age, the reproductive capacity of female rats begins to decline. Whether there are consequences for social and reproductive behaviors…
Read on PubMed• November 2011
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Inhibition Of 5α-Reductase Activity In Late Pregnancy Decreases Gestational Length And Fecundity And Impairs Object Memory And Central Progestogen Milieu Of Juvenile Rat Offspring
Psychological, physical and/or immune stressors during pregnancy are associated with negative birth outcomes, such as preterm birth and developmental abnormalities.…
Read on PubMed• November 2011
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Immune Stress In Late Pregnant Rats Decreases Length Of Gestation And Fecundity, And Alters Later Cognitive And Affective Behaviour Of Surviving Pre-Adolescent Offspring
Immune challenge during pregnancy is associated with preterm birth and poor perinatal development. The mechanisms of these effects are not…
Read on PubMed• November 2011
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Prenatal Stress Alters Progestogens To Mediate Susceptibility To Sex-Typical, Stress-Sensitive Disorders, Such As Drug Abuse: A Review
Maternal-offspring interactions begin prior to birth. Experiences of the mother during gestation play a powerful role in determining the developmental…
Read on PubMed• October 2011
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Association Of Common Variants In The Human Eyes Shut Ortholog (EYS) With Statin-Induced Myopathy: Evidence For Additional Functions Of EYS
Of the nearly 38 million people in the USA who receive statin therapy, 0.1-0.5% experience severe or life-threatening myopathic side…
Read on PubMed• October 2011
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Alzheimer Disease Pathology In Subjects Without Dementia In 2 Studies Of Aging: The Nun Study And The Adult Changes In Thought Study
Individuals with antemortem preservation of cognition who show autopsy evidence of at least moderate Alzheimer disease (AD) pathology suggest the…
Read on PubMed• October 2011
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Role Of Cerebrospinal Fluid And Plasma Biomarkers In The Diagnosis Of Neurodegenerative Disorders And Mild Cognitive Impairment
Biomarkers are one type of laboratory testing being developed in response to the therapeutic imperative for diseases that cause cognitive…
Read on PubMed• October 2011
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White Matter Lesions Defined By Diffusion Tensor Imaging In Older Adults
The cellular and molecular mechanisms underlying magnetic resonance imaging-defined white matter (WM) changes associated with age-related cognitive decline remain poorly…
Read on PubMed• September 2011