Featured Publications
About Our Research
We’ve doubled down on our commitment to research and teaching.
Arkana is a learning, teaching, and innovating practice with one unifying passion – to actively work toward the day that our research yields breakthroughs that make our services unnecessary. Eradicating rare and common diseases is the end game of all of our efforts because patient health is foremost in our minds every day. Read about some of our latest publications below.
All Publications
(475 Results)
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Dual Diagnosis Of Histiocytoid Sweet Syndrome And Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Histiocytoid Sweet syndrome (H-SS) is a rare variant of acute febrile neutrophilic dermatosis. It isfrequently associated with hematologic malignancies but…
Read on JAAD• May 2022
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Collapsing Glomerulopathy In A Patient With Mixed Connective Tissue Disease
Collapsing glomerulopathy (CG) is a form of podocytopathy that is challenging to manage. CG can be idiopathic or associated with…
Read on PubMed• April 2022
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6,5-Fused Ring, C2-Salvinorin Ester, Dual Kappa And Mu Opioid Receptor Agonists As Analgesics Devoid Of Anxiogenic Effects
Current common analgesics are mediated through the mu or kappa opioid receptor agonism. Unfortunately, selective mu or kappa receptor agonists…
Read on PubMed• April 2022
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High-Speed Light-Sheet Microscopy For The In-Situ Acquisition Of Volumetric Histological Images Of Living Tissue
Histological examinations typically require the excision of tissue, followed by its fixation, slicing, staining, mounting and imaging, with timeframes ranging…
Read on PubMed• March 2022
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Ext1 And Ncam1-Associated Membranous Lupus Nephritis In A Cohort Of Patients Undergoing Repeat Kidney Biopsies
EXT1/2 and NCAM1 associated membranous lupus nephritis (MLN) may represent distinct disease phenotypes with prognostic significance.
Read on PubMed• March 2022
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Cell Type-Specific Mechanistic Target Of Rapamycin-Dependent Distortion Of Autophagy Pathways In Lupus Nephritis
Pro-inflammatory immune system development, metabolomic defects, and deregulation of autophagy play interconnected roles in driving the pathogenesis of systemic lupus…
Read on PubMed• March 2022
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Cubilin And Amnionless Protein Are Novel Target Antigens in Anti–Brush Border Antibody Disease
The kidney proximal tubule reabsorbs large amounts of low-molecular-weight proteins, albumin, electrolytes, and solutes from the glomerular filtrate to the…
Read on Kidney International• March 2022
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Clinicopathologic features of non-lupus membranous nephropathy in a pediatric population
Membranous nephropathy is an uncommon cause of nephrotic syndrome in pediatrics.
Read on PubMed• March 2022
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Antibody-Suppressor Cxcr5 + Cd8 + T Cellular Therapy Ameliorates Antibody-Mediated Rejection Following Kidney Transplant In Ccr5 Ko Mice
CCR5 KO kidney transplant (KTx) recipients are extraordinarily high alloantibody producers and develop pathology that mimics human antibody-mediated rejection (AMR).
Read on PubMed• February 2022
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Llopregnanolone And Neurohiv: Potential Benefits Of Neuroendocrine Modulation In The Era Of Antiretroviral Therapy
Forty years into the HIV pandemic, approximately 50% of infected individuals still suffer from a constellation of neurological disorders collectively…
Read on PubMed• February 2022