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Ring Fiber

By Joshua Sonnen, MD

Sep 11, 2024

Clinical History

What is the finding in these electron micrographs and what is its clinical association?

A. Ouroboros fiber – necrotizing myopathy

B. Fibrous body – myofibrillar myopathy

C. Ringbindung – myotonic dystrophy

D. Target fiber – neurogenic atrophy

Ring Fiber

Correct Answer

Ring fiber (also known as Ringbindung)

Ring fibers are a classical finding in myotonic dystrophy but is a may be seen in various chronic myopathies. They may represent a nonspecific feature of muscle fiber regeneration.

 

Reference

https://neuromuscular.wustl.edu/pathol/ring.htm

 

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